Key role of a structural water molecule for the specificity of 14F7-An antitumor antibody targeting the NeuGc GM3 ganglioside

Kaare Bjerregaard-Andersen, Fana Abraha, Hedda Johannesen, Stefan Oscarson, Ernesto Moreno, Ute Krengel

Research output: Contribution to journalArticlepeer-review

4 Scopus citations
Original languageEnglish
Pages (from-to)1500-1509
JournalGlycobiology
Volume31
Issue number11
DOIs
StatePublished - Nov 2021

Keywords

  • carbohydrate-antibody interactions
  • protein-carbohydrate interactions
  • water-mediated antibody specificity
  • water-mediated interaction
  • X-ray crystal structure

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